Review on Fabrication and Application of Regenerated <i>Bombyx mori</i> Silk Fibroin Materials

Abstract Natural silk fiber derived from the Bombyx mori (B. mori) silkworm has long been used as a luxury raw material in textile industry because of its shimmering appearance and durability, surgical suture for high strength flexibility. Regenerated fibroin, main protein extracted cocoons B. silkworm, recently gained considerable attention due to outstanding properties, including facile processability, superior biocompatibility, controllable biodegradation, versatile functionalization. Tremendous effort made fabricate fibroin into various promising materials with controlled structural functional characteristics advanced utilities multitude biomedical applications, flexible optics, electronics devices, filtration systems. Herein, reverse engineered extraction methods are reviewed, recent advances techniques discussed. Fabrication formats also addressed detail; particular, progress new fabrication technologies is presented. Attractive applications fibroin-based then summarized highlighted. The challenges faced by current approaches production future directions acquired pushing these favorable further toward above mentioned elaborated.